{"id":82652,"date":"2023-06-30T00:45:15","date_gmt":"2023-06-30T00:45:15","guid":{"rendered":"https:\/\/cred.ai\/news\/?p=82652"},"modified":"2023-10-24T16:58:19","modified_gmt":"2023-10-24T16:58:19","slug":"first-ever-ai-generated-drug-enters-phase-ii-clinical-trials","status":"publish","type":"post","link":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/","title":{"rendered":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials"},"content":{"rendered":"<p class=\"p1\">Insilico Medicine, a biotech company based in Hong Kong, has unveiled the first-ever medicine completely developed using artificial intelligence (AI). The drug, code-named INS018_055, has been engineered to combat idiopathic pulmonary fibrosis, a long-term disease responsible for extensive lung scarring. It is now set to enter clinical trials with human subjects, as reported by <a href=\"https:\/\/www.cnbc.com\/2023\/06\/29\/ai-generated-drug-begins-clinical-trials-in-human-patients.html\">CNBC<\/a>.<\/p>\n<blockquote><p>\u201cIt is the first fully generative AI drug to reach human clinical trials, and specifically Phase II trials with patients,\u201d Alex Zhavoronkov, founder and CEO of Insilico Medicine, said. \u201cWhile there are other AI-designed drugs in trials, ours is the first drug with both a novel AI-discovered target and a novel AI-generated design.\u201d<\/p><\/blockquote>\n<p class=\"p1\">Idiopathic pulmonary fibrosis has grown more prevalent in recent years. It now affects approximately 100,000 individuals nationwide, and an estimated five million people globally. If left untreated, the disease can prove fatal within two to five years, according to the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8739228\/#:~:text=Idiopathic%20pulmonary%20fibrosis%20(IPF)%20is,of%20acute%20exacerbation%20(2).\">National Institutes of Health<\/a>.<\/p>\n<p class=\"p1\">Insilico Medicine initially focused on idiopathic pulmonary fibrosis given its significant impact on the aging process, but the company is simultaneously developing two other drugs that are partially created using AI. One of them works to counteract Covid-19 and is currently in Phase I of clinical trials. The other, a cancer drug considered a &#8220;USP1 inhibitor for the treatment of solid tumors,&#8221; has recently received FDA approval, giving Insilico Medicine the green light to commence clinical trials for that drug as well.<\/p>\n<blockquote><p>\u201cWhen this company was launched, we were focused on algorithms \u2014 developing the technology that could discover and design new molecules,\u201d Zhavoronkov said. \u201cI never imagined in those early days that I would be taking my own AI drugs into clinical trials with patients. But we realized that in order to validate our AI platform, we needed to not only design a new drug for a new target, but bring it into clinical trials to prove that our technology worked.\u201d<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Insilico Medicine, a biotech company based in Hong Kong, has unveiled the first-ever medicine completely developed using artificial intelligence (AI). The drug, code-named INS018_055, has been engineered to combat idiopathic pulmonary fibrosis, a long-term disease responsible for extensive lung scarring. It is now set to enter clinical trials with human subjects, as reported by CNBC. &#8230;<\/p>\n","protected":false},"author":14,"featured_media":82655,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[204],"tags":[114,665,913,914],"class_list":["post-82652","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-news","tag-ai","tag-drug","tag-pharmaceutical"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>First-Ever AI-Generated Drug Enters Phase II Clinical Trials - crednews<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"First-Ever AI-Generated Drug Enters Phase II Clinical Trials\" \/>\n<meta property=\"og:description\" content=\"Insilico Medicine, a biotech company based in Hong Kong, has unveiled the first-ever medicine completely developed using artificial intelligence (AI). The drug, code-named INS018_055, has been engineered to combat idiopathic pulmonary fibrosis, a long-term disease responsible for extensive lung scarring. It is now set to enter clinical trials with human subjects, as reported by CNBC. ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/\" \/>\n<meta property=\"og:site_name\" content=\"crednews\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-30T00:45:15+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-10-24T16:58:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341-1024x576.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"cred.ai staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cred.ai staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/\"},\"author\":{\"name\":\"cred.ai staff\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/#\\\/schema\\\/person\\\/b8132cf694e343ab4c8bd8a3da99e9c2\"},\"headline\":\"First-Ever AI-Generated Drug Enters Phase II Clinical Trials\",\"datePublished\":\"2023-06-30T00:45:15+00:00\",\"dateModified\":\"2023-10-24T16:58:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/\"},\"wordCount\":320,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cred.ai\\\/news\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/shutterstock_2225555341.png\",\"keywords\":[\"news\",\"AI\",\"drug\",\"pharmaceutical\"],\"articleSection\":[\"Health\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/\",\"url\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/\",\"name\":\"First-Ever AI-Generated Drug Enters Phase II Clinical Trials - crednews\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cred.ai\\\/news\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/shutterstock_2225555341.png\",\"datePublished\":\"2023-06-30T00:45:15+00:00\",\"dateModified\":\"2023-10-24T16:58:19+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/#\\\/schema\\\/person\\\/b8132cf694e343ab4c8bd8a3da99e9c2\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#primaryimage\",\"url\":\"https:\\\/\\\/cred.ai\\\/news\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/shutterstock_2225555341.png\",\"contentUrl\":\"https:\\\/\\\/cred.ai\\\/news\\\/wp-content\\\/uploads\\\/2023\\\/07\\\/shutterstock_2225555341.png\",\"width\":2048,\"height\":1152,\"caption\":\"greenbutterfly via Shutterstock\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/2023\\\/06\\\/30\\\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/cred.ai\\\/news\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"First-Ever AI-Generated Drug Enters Phase II Clinical Trials\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/#website\",\"url\":\"https:\\\/\\\/cred.ai\\\/news\\\/\",\"name\":\"crednews\",\"description\":\"a division of cred.ai\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cred.ai\\\/news\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/cred.ai\\\/news\\\/#\\\/schema\\\/person\\\/b8132cf694e343ab4c8bd8a3da99e9c2\",\"name\":\"cred.ai staff\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g\",\"caption\":\"cred.ai staff\"},\"url\":\"https:\\\/\\\/cred.ai\\\/news\\\/author\\\/lillycred-ai\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials - crednews","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/","og_locale":"en_US","og_type":"article","og_title":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials","og_description":"Insilico Medicine, a biotech company based in Hong Kong, has unveiled the first-ever medicine completely developed using artificial intelligence (AI). The drug, code-named INS018_055, has been engineered to combat idiopathic pulmonary fibrosis, a long-term disease responsible for extensive lung scarring. It is now set to enter clinical trials with human subjects, as reported by CNBC. ...","og_url":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/","og_site_name":"crednews","article_published_time":"2023-06-30T00:45:15+00:00","article_modified_time":"2023-10-24T16:58:19+00:00","og_image":[{"width":1024,"height":576,"url":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341-1024x576.png","type":"image\/png"}],"author":"cred.ai staff","twitter_card":"summary_large_image","twitter_misc":{"Written by":"cred.ai staff","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#article","isPartOf":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/"},"author":{"name":"cred.ai staff","@id":"https:\/\/cred.ai\/news\/#\/schema\/person\/b8132cf694e343ab4c8bd8a3da99e9c2"},"headline":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials","datePublished":"2023-06-30T00:45:15+00:00","dateModified":"2023-10-24T16:58:19+00:00","mainEntityOfPage":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/"},"wordCount":320,"commentCount":0,"image":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#primaryimage"},"thumbnailUrl":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341.png","keywords":["news","AI","drug","pharmaceutical"],"articleSection":["Health"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/","url":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/","name":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials - crednews","isPartOf":{"@id":"https:\/\/cred.ai\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#primaryimage"},"image":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#primaryimage"},"thumbnailUrl":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341.png","datePublished":"2023-06-30T00:45:15+00:00","dateModified":"2023-10-24T16:58:19+00:00","author":{"@id":"https:\/\/cred.ai\/news\/#\/schema\/person\/b8132cf694e343ab4c8bd8a3da99e9c2"},"breadcrumb":{"@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#primaryimage","url":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341.png","contentUrl":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341.png","width":2048,"height":1152,"caption":"greenbutterfly via Shutterstock"},{"@type":"BreadcrumbList","@id":"https:\/\/cred.ai\/news\/2023\/06\/30\/first-ever-ai-generated-drug-enters-phase-ii-clinical-trials\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/cred.ai\/news\/"},{"@type":"ListItem","position":2,"name":"First-Ever AI-Generated Drug Enters Phase II Clinical Trials"}]},{"@type":"WebSite","@id":"https:\/\/cred.ai\/news\/#website","url":"https:\/\/cred.ai\/news\/","name":"crednews","description":"a division of cred.ai","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cred.ai\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/cred.ai\/news\/#\/schema\/person\/b8132cf694e343ab4c8bd8a3da99e9c2","name":"cred.ai staff","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/0a4fea4aa3858da7e3fb753cee34170b27382926ecb015a1f13c09ef27f883d8?s=96&d=mm&r=g","caption":"cred.ai staff"},"url":"https:\/\/cred.ai\/news\/author\/lillycred-ai\/"}]}},"featured_image":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/07\/shutterstock_2225555341-768x432.png","youtube_link":null,"vimeo_link":null,"trailer_link":null,"video_link":null,"video_type":null,"author_name":"cred.ai staff","categories_name":["Health"],"preview_image":"https:\/\/cred.ai\/news\/wp-content\/uploads\/2023\/06\/lungs-vert.png","custom_author":"crednews staff","_links":{"self":[{"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/posts\/82652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/comments?post=82652"}],"version-history":[{"count":0,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/posts\/82652\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/media\/82655"}],"wp:attachment":[{"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/media?parent=82652"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/categories?post=82652"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cred.ai\/news\/wp-json\/wp\/v2\/tags?post=82652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}